HXT12/YIL170W Locus History Help

Sequence Annotation Notes
DateNote
2001-10-16In 1999, Wieczorke EA, et al reported finding "that all of the Hxt proteins but Hxt12 are able to transport at least one of the different hexoses and permit growth of the hxt1-17 gal2 deletion strain" and that they "were not able to functionally express Hxt12, supporting the view that HXT12 is a pseudogene". They give two references for this statement:
B. Andre, Yeast 11 (1995) 1575-1611
A.L. Kruckeberg, Arch. Microbiol. 166 (1996) 283-292


Wieczorke R, et al.  (1999) Concurrent knock-out of at least 20 transporter genes is required to block uptake of hexoses in Saccharomyces cerevisiae. FEBS Lett 464(3):123-8
Andre B  (1995) An overview of membrane transport proteins in Saccharomyces cerevisiae. Yeast 11(16):1575-611
Kruckeberg AL  (1996) The hexose transporter family of Saccharomyces cerevisiae. Arch Microbiol 166(5):283-92
2001-10-16This note regarding the HXT12 locus was published in A.L. Kruckeberg, Arch. Microbiol. 166 (1996) 283-292:
ORFs YIL170w and YIL171w have been combined by deletion of two nucleotides to yield the predicted protein Hxt12. The DNA sequence represents either a pseudogene or a sequencing error.


Kruckeberg AL  (1996) The hexose transporter family of Saccharomyces cerevisiae. Arch Microbiol 166(5):283-92