FHL1/YPR104C Locus History Help


Nomenclature History
Standard Name Reference
FHL1 Hermann-Le Denmat S, et al.  (1994) Suppression of yeast RNA polymerase III mutations by FHL1, a gene coding for a fork head protein involved in rRNA processing. Mol Cell Biol 14(5):2905-13
Other Name(s)Reference
SPP42 Maddock JR, et al.  (1994) Extragenic suppressors of Saccharomyces cerevisiae prp4 mutations identify a negative regulator of PRP genes. Genetics 136(3):833-47 Maddock J  (1990) Genetic interactions among yeast gene products required for messenger RNA processing. Ph.D. thesis, Carnegie Mellon University, United States
Sequence Annotation Notes
DateNote
2003-12-01Based on the automated comparison of closely related Saccharomyces species, Kellis et al. suggest that the stop site for FHL1/YPR104C be moved 44 nt downstream. This suggestion was reviewed by SGD curators, but will not be incorporated until supported by experimental data. The reason(s) for this decision are as follows: 1) The sequence analysis is inconclusive because the N-terminal sequence of this protein seems particularly divergent, and none of the available Saccharomyces species share exactly the same stop site. The difference in S. cerevisiae is most likely simply normal species variation.

Kellis M, et al.  (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54