RAD53/YPL153C Locus History

Nomenclature History
Standard Name	Reference
RAD53	Sitney, K. (1989) Personal Communication, Mortimer Map Edition 10

Nomenclature History Notes
Date	Note
2003-12-09	SAD1 has been used to refer to both RAD53/YPL153C, a checkpoint protein involved in DNA repair, and SAD1/YFR005C, a protein involved in mRNA splicing.

Other Notes
Date	Note
2013-05-01	Chen YC, et al. (2013) sequenced the rad53-1 allele and found a single G653E point mutation, which is identical to that reported for rad53-11.
	Weinert TA, et al. (1994) Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev 8(6):652-65
	Dohrmann PR and Sclafani RA (2006) Novel role for checkpoint Rad53 protein kinase in the initiation of chromosomal DNA replication in Saccharomyces cerevisiae. Genetics 174(1):87-99
	Chen YC, et al. (2013) DNA Replication Checkpoint Signaling Depends on a Rad53-Dbf4 N-terminal Interaction in Saccharomyces cerevisiae. Genetics ()

Mapping Notes
Date	Note
1996-09-21	Edition 13: RAD53 has also been referred to as SAD1, but should not be confused with the SAD1 gene on chromosome III that appears to be involved in SnRNP assembly.
	Cherry JM, et al. (1996) "Genetic and Physical Maps of Saccharomyces cerevisiae (Edition 13)". Pp. 361-364 in 1996 Yeast Genetics and Molecular Biology Meeting Program and Abstracts. Bethesda, MD: The Genetics Society of America
1997-10-20	Edition 14: Although RAD53 has also been called SPK1, it is unrelated to the S. pombe SPK1 gene
	Cherry JM, et al. (1997) Genetic and physical maps of Saccharomyces cerevisiae. Nature 387(6632 Suppl):67-73