MIP1/YOR330C Locus History Help


Nomenclature History
Standard Name Reference
MIP1 Foury F  (1989) Cloning and sequencing of the nuclear gene MIP1 encoding the catalytic subunit of the yeast mitochondrial DNA polymerase. J Biol Chem 264(34):20552-60
Other Name(s)Reference
mitochondrial DNA polymerase catalytic subunit Foury F  (1989) Cloning and sequencing of the nuclear gene MIP1 encoding the catalytic subunit of the yeast mitochondrial DNA polymerase. J Biol Chem 264(34):20552-60
Nomenclature History Notes
DateNote
2003-12-09MIP1 has been used to refer to both MIP1/YOR330C, which encodes the mitochondrial DNA polymerase, and OCT1/YKL134C, which encodes the mitochondrial intermediate peptidase.
Sequence Annotation Notes
DateNote
2005-11-30Based on 5' end mapping published by Francoise Foury, the start site for MIP1/YOR330C was moved 78 nt (26 codons) downstream.

Foury F  (1989) Cloning and sequencing of the nuclear gene MIP1 encoding the catalytic subunit of the yeast mitochondrial DNA polymerase. J Biol Chem 264(34):20552-60
Other Notes
DateNote
2009-09-21The MIP1 gene is polymorphic in different S. cerevisiae strains, carrying an alanine codon at position 661 in the S288C and W303 backgrounds, and a threonine codon at position 661 in the RM11-1a, SK1, and Sigma1278b backgrounds. The two alleles have differing effects on mitochondrial genome stability.

Dimitrov LN, et al.  (2009) Polymorphisms in multiple genes contribute to the spontaneous mitochondrial genome instability of Saccharomyces cerevisiae S288C strains. Genetics 183(1):365-83
Mapping Notes
DateNote
1997-10-20Edition 14: The name MIP1 has also been used to refer to YKL134c encoding a mitochondrial intermediate peptidase

Cherry JM, et al.  (1997) Genetic and physical maps of Saccharomyces cerevisiae. Nature 387(6632 Suppl):67-73