MGM1/YOR211C Locus History Help


Nomenclature History
Standard Name Reference
MGM1 SGD  (2007) Information without a citation in SGD ()
Nomenclature History Notes
DateNote
2003-12-09TPM2 has been used to refer to both MGM1/YOR211C, which encodes a mitochondrial dynamin-related GTPase, and to TPM2/YIL138C, which encodes tropomyosin 2.
Sequence Annotation Notes
DateNote
2008-11-04Data from Nagalakshmi et al. 2008 suggest that there is an in-frame AUG 21 codons upstream of the currently annotated AUG for either all or some of the transcripts of MGM1/YOR211C. The upstream AUG represents the previously annotated start for this ORF; the annotation of which was changed based on genetic analyses done by Shepard K.A. et al. (1999).

Shepard KA and Yaffe MP  (1999) The yeast dynamin-like protein, Mgm1p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritance. J Cell Biol 144(4):711-20
Nagalakshmi U, et al.  (2008) The transcriptional landscape of the yeast genome defined by RNA sequencing. Science 320(5881):1344-9
2006-10-03Based on genetic analyses done by Shepard K.A. et al. (1999), the start site for MGM1/YOR211C has been moved 63 bp (21 codons) downstream. The numbering for both the nucleotides in the DNA coding sequence and the amino acids in the predicted protein have been changed accordingly. Special thanks to Ivo Pedruzzi and the team at Swiss-Prot for bringing this change to our attention.

Shepard KA and Yaffe MP  (1999) The yeast dynamin-like protein, Mgm1p, functions on the mitochondrial outer membrane to mediate mitochondrial inheritance. J Cell Biol 144(4):711-20
Mapping Notes
DateNote
1997-10-20Edition 14: MGM1 has also been called TPM2, not to be confused with TPM2 encoding tropomyosin isoform 2 on chromosome IX

Cherry JM, et al.  (1997) Genetic and physical maps of Saccharomyces cerevisiae. Nature 387(6632 Suppl):67-73