HRT1/YOL133W Locus History Help


Nomenclature History
Standard Name Reference
HRT1 Seol JH, et al.  (1999) Cdc53/cullin and the essential Hrt1 RING-H2 subunit of SCF define a ubiquitin ligase module that activates the E2 enzyme Cdc34. Genes Dev 13(12):1614-26
Other Name(s)Reference
ROC1 Ohta T, et al.  (1999) ROC1, a homolog of APC11, represents a family of cullin partners with an associated ubiquitin ligase activity. Mol Cell 3(4):535-41
Nomenclature History Notes
DateNote
2003-12-09Both HRT1/RBX1/ROC1/YOL133W and HRT2/YMR027W have been referred to as HRT2. In Swaroop et al (2000) Oncogene 19:2855-66, YOL133W is referred to as HRT2.
Mapping Notes
DateNote
1997-10-20Edition 14: The Hrt1p localizes to the nucleolus by indirect immunofluoresence with antibodies made against recombinant Hrt1p. Mutants in the Ring-h2 finger are dominant in heterozygous diploid yeast in a chromosomal context. These mutants have altered nucleolar structure and are both cold sensitive and temperature sensitive. The dominant mutants have nuclear segregation defects.

Cherry JM, et al.  (1997) Genetic and physical maps of Saccharomyces cerevisiae. Nature 387(6632 Suppl):67-73
1998-11-10Edition 15: HRT1 has also been referred to as ROC1; do not confuse with TEC1/YBR083W on chromosome II, which has also been called ROC1.

Cherry JM, et al.  (1998) "Genetic and Physical Maps of Saccharomyces cerevisiae (Edition 15)". Pp. 414-420 in 1998 Yeast Genetics and Molecular Biology Meeting Program and Abstracts. Bethesda, MD: The Genetics Society of America