RAV1/YJR033C Locus History Help


Nomenclature History
An SGD Standard Name was first assigned to this gene on 2001-07-02.
Standard Name Reference
RAV1 Seol JH, et al.  (2001) Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nat Cell Biol 3(4):384-91
Other Name(s)Reference
SOI3 Redding K, et al.  (1996) Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins. Mol Cell Biol 16(11):6208-17 Sipos G, et al.  (2004) Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteins. Mol Biol Cell 15(7):3196-209
Nomenclature History Notes
DateNote
2004-11-23Suppressor of the rapid onset of impotence (SOI3) was found to allelic with RAV1/YJR033C, as reported by Robert S. Fuller and published in Sipos, G et al. (2004) Mol Biol Cell 15(7):3196-209.

Sipos G, et al.  (2004) Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteins. Mol Biol Cell 15(7):3196-209
Mapping Notes
DateNote
1996-09-21Edition 13: Comments provided by J. Brickner: Suppressor of the rapid Onset of Impotence (SOI3) observed after shutting off the Kex2p localization-defective mutant Tyr713Ala. Mutations in the cytosolic tail of Kex2p, either deletion of the tail or substitution of Alanine for Tyr713, result in loss of TGN localization. Loss of Golgi retention results in a more rapid loss of mating competence of Mat alpha cells after shutting off expression of a GAL1 promoter-driven form of KEX2-Y713A. soi3 mutants suppress the localization defect in Kex2p-Y713A and, unlike the parent strain, can mate well after 7h on glucose.

Cherry JM, et al.  (1996) "Genetic and Physical Maps of Saccharomyces cerevisiae (Edition 13)". Pp. 361-364 in 1996 Yeast Genetics and Molecular Biology Meeting Program and Abstracts. Bethesda, MD: The Genetics Society of America