XRN1/YGL173C Locus History

Nomenclature History
Standard Name	Reference
XRN1	Larimer FW and Stevens A (1990) Disruption of the gene XRN1, coding for a 5'----3' exoribonuclease, restricts yeast cell growth. Gene 95(1):85-90

Other Name(s)	Reference
KEM1	Kim J, et al. (1990) kem mutations affect nuclear fusion in Saccharomyces cerevisiae. Genetics 126(4):799-812
SKI1	Toh-E A, et al. (1978) Chromosomal superkiller mutants of Saccharomyces cerevisiae. J Bacteriol 136(3):1002-7

Nomenclature History Notes
2011-07-27	This gene was originally named KEM1 (Kar-Enhancing Mutations). The name was changed to XRN1 (eXoRiboNuclease) based on a request (July 2011) from the community. The rationale being that researchers use the name XRN1 much more frequently when referring to YGL173C in the literature, the name XRN1 is more consistent with this gene product's role in vivo, and that the name XRN1 is the one used for the equivalent gene product in other organisms.

Nomenclature History Notes

Date

Note

2011-07-27

This gene was originally named KEM1 (Kar-Enhancing Mutations). The name was changed to XRN1 (eXoRiboNuclease) based on a request (July 2011) from the community. The rationale being that researchers use the name XRN1 much more frequently when referring to YGL173C in the literature, the name XRN1 is more consistent with this gene product's role in vivo, and that the name XRN1 is the one used for the equivalent gene product in other organisms.

Mapping Notes
Date	Note
1992-10-01	Edition 11: dst2 and kem1 are allelic; these genes are also allelic to sep1 and xrn1
	Mortimer RK, et al. (1992) Genetic and physical maps of Saccharomyces cerevisiae, Edition 11. Yeast 8(10):817-902
1992-10-01	Edition 11: kem1 and kem3 data are not internally consistent nor are they consistent with other data for the lys5-met13 interval. The positions chosen for these genes are tentative.
	Mortimer RK, et al. (1992) Genetic and physical maps of Saccharomyces cerevisiae, Edition 11. Yeast 8(10):817-902