HEM2/YGL040C Locus History Help

Nomenclature History
Standard Name Reference
HEM2 Myers AM, et al.  (1987) Characterization of the yeast HEM2 gene and transcriptional regulation of COX5 and COR1 by heme. J Biol Chem 262(35):16822-9
Other Name(s)Reference
OLE4 Gollub EG, et al.  (1977) Yeast mutants deficient in heme biosynthesis and a heme mutant additionally blocked in cyclization of 2,3-oxidosqualene. J Biol Chem 252(9):2846-54 Bard M  (1972) Biochemical and genetic aspects of nystatin resistance in saccharomyces cerevisiae. J Bacteriol 111(3):649-57
SLU1 Gachotte D, et al.  (1997) A yeast sterol auxotroph (erg25) is rescued by addition of azole antifungals and reduced levels of heme. Proc Natl Acad Sci U S A 94(21):11173-8
Nomenclature History Notes
2003-12-09SLU1 has been used in the literature to refer to both HEM2/YGL040C, which encodes a porphobilinogen synthase and SLU1, which is essential for splicing.
Mapping Notes
1994-08-01Edition 12: HEM2/YGL040C [delta-aminolevulinate dehydratase] has also been called SLU1, but it should not be confused with the gene by that name that is synergistically lethal with U5 snRNA.

Mortimer RK, et al.  (1994) "Genetic and Physical maps of Saccharomyces cerevisiae (Edition 12)". Pp. 374-377 in 1994 Yeast Genetics and Molecular Biology Meeting Program and Abstracts. Bethesda, MD: The Genetics Society of America