FUN19/YAL034C Locus History Help

Nomenclature History
Standard Name Reference
FUN19 Diehl BE and Pringle JR  (1991) Molecular analysis of Saccharomyces cerevisiae chromosome I: identification of additional transcribed regions and demonstration that some encode essential functions. Genetics 127(2):287-98
Sequence Annotation Notes
2003-09-22The start site of FUN19/YAL034C was moved 150 nt (50 codons) downstream, based on the automated comparison of closely-related Saccharomyces species by Kellis et al. 2003. The numbering for both the nucleotides in the DNA coding sequence and the amino acids in the predicted protein have been updated. Evidence supporting this change includes: 1) This is the predicted start methionine in the majority of Saccharomyces species orthologs analyzed by Kellis et al. and/or Cliften et al.; 2) Significant sequence conservation begins abruptly at this predicted start methionine.

Kellis M, et al.  (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54
Cliften P, et al.  (2003) Finding functional features in Saccharomyces genomes by phylogenetic footprinting. Science 301(5629):71-6
Mapping Notes
1992-10-01Edition 11: transcribed region physically mapped in relation to transcripts of already mapped genes on the left arm distal to mak9

Mortimer RK, et al.  (1992) Genetic and physical maps of Saccharomyces cerevisiae, Edition 11. Yeast 8(10):817-902
2012-08-21The section of the left arm of Chromosome I spanning YAL023C to YAL062W and the section of the right arm of Chromosome XV spanning YOR321W to YOR375C represent paralogous segments that arose from the whole genome duplication. These regions contain the following pairs of paralogous genes:

YAL023C/PMT2 and YOR321W/PMT3
YAL028W/FRT2 and YOR324C/FRT1
YAL029C/MYO4 and YOR326W/MYO2
YAL030W/SNC1 and YOR327C/SNC2
YAL034C/FUN19 and YOR338W
YAL037W and YOR342C
YAL038W/CDC19 and YOR347C/PYK2
YAL051W/OAF1 and YOR363C/PIP2
YAL053W/FLC2 and YOR365C
YAL056W/GPB2 and YOR371C/GPB1
YAL062W/GDH3 and YOR375C/GDH1

Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61