HAC1/YFL031W Locus History Help


Nomenclature History
Standard Name Reference
HAC1 Mori K, et al.  (1996) Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway. Genes Cells 1(9):803-17
Other Name(s)Reference
ERN4 Mori K, et al.  (1996) Signalling from endoplasmic reticulum to nucleus: transcription factor with a basic-leucine zipper motif is required for the unfolded protein-response pathway. Genes Cells 1(9):803-17
IRE15 Nikawa J, et al.  (1997) Suppression of the Saccharomyces cerevisiae hac1/ire15 mutation by yeast genes and human cDNAs. Gene 201(1-2):5-10
Sequence Annotation Notes
DateNote
2003-12-02Based on comparison with related fungi, Kellis et al. propose that YFL032W and YFL031W be merged into a single, larger ORF. SGD has re-sequenced this segment of the chromosome, in S288C, and confirmed the presence of an in-frame stop codon between these two ORFs. Although it is possible that these ORFs are merged in other strains of S. cerevisiae, the systematic sequence will not be changed.

Kellis M, et al.  (2003) Sequencing and comparison of yeast species to identify genes and regulatory elements. Nature 423(6937):241-54
2001-05-29A single C was inserted after the C at chromosomal coordinate 75751 (see GenBank file YSCCHRVIN). In addition, a new intron was annotated at relative coordinates 662-913. As a result, the chromosomal coordinates for ORF YFL031W are now 75177-75837..76090-76145, with relative coordinates 1-661..914-969. The old chromosomal coordinates for YFL031W were 75178-75780, with old relative coordinates 1-603.
Old: 75721 AACAACAATTTGTTTGATGCGGTGGCCTCGC-GTTGGCAGACCCACTCTGCGACGATATA 75779
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New: 75720 AACAACAATTTGTTTGATGCGGTGGCCTCGCCGTTGGCAGACCCACTCTGCGACGATATA 75779