DID4/YKL002W Locus History Help


Nomenclature History
An SGD Standard Name was first assigned to this gene on 2000-10-23.
Standard Name Reference
DID4 Amerik AY, et al.  (2000) The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol Biol Cell 11(10):3365-80
Other Name(s)Reference
CHM2 Howard TL, et al.  (2001) CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins. J Cell Sci 114(Pt 13):2395-404
GRD7 Nothwehr SF, et al.  (1996) The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins. Mol Cell Biol 16(6):2700-7
REN1 Davis NG, et al.  (1993) Cis- and trans-acting functions required for endocytosis of the yeast pheromone receptors. J Cell Biol 122(1):53-65
VPL2 Rothman JH and Stevens TH  (1986) Protein sorting in yeast: mutants defective in vacuole biogenesis mislocalize vacuolar proteins into the late secretory pathway. Cell 47(6):1041-51
VPS14 Raymond CK, et al.  (1992) Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants. Mol Biol Cell 3(12):1389-402
VPS2 Robinson JS, et al.  (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48 Rothman JH, et al.  (1989) Characterization of genes required for protein sorting and vacuolar function in the yeast Saccharomyces cerevisiae. EMBO J 8(7):2057-65
VPT14 Robinson JS, et al.  (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48
Nomenclature History Notes
DateNote
2001-10-25DID4/YKL002W has been shown to be allelic to two unmapped loci, VPS2 and REN1. VPS2 and REN1 are now aliases for DID4/YKL002W. (Personal communication from Kate Bowers, University of Oregon).

Amerik AY, et al.  (2000) The Doa4 deubiquitinating enzyme is functionally linked to the vacuolar protein-sorting and endocytic pathways. Mol Biol Cell 11(10):3365-80
Rothblatt et al.  (1994) Guidebook to the Secretory Pathway
Sequence Annotation Notes
DateNote
2000-07-22The start site of YKL002W was moved 243 bp upstream, and a 68-bp intron was added at relative coordinates 61-128.