GGC1/YDL198C Summary Help

Standard Name GGC1 1
Systematic Name YDL198C
Alias YHM1 2 , SHM1 3
Feature Type ORF, Verified
Description Mitochondrial GTP/GDP transporter; essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family (2)
Name Description GDP/GTP Carrier 1
Chromosomal Location
ChrIV:104551 to 103649 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All GGC1 GO evidence and references
  View Computational GO annotations for GGC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 9 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
27 total interaction(s) for 21 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 6
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 2
  • PCA: 6

Genetic Interactions
  • Dosage Lethality: 1
  • Dosage Rescue: 1
  • Phenotypic Enhancement: 3
  • Phenotypic Suppression: 1
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 300
Molecular Weight (Da) 33,215
Isoelectric Point (pI) 10.84
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrIV:104551 to 103649 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..903 104551..103649 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000002357
References cited on this page View Complete Literature Guide for GGC1
1) Vozza A, et al.  (2004) Identification of the mitochondrial GTP/GDP transporter in Saccharomyces cerevisiae. J Biol Chem 279(20):20850-7
2) Lesuisse E, et al.  (2004) Role of YHM1, encoding a mitochondrial carrier protein, in iron distribution of yeast. Biochem J 378(Pt 2):599-607
3) Kao LR, et al.  (1996) SHM1: a multicopy suppressor of a temperature-sensitive null mutation in the HMG1-like abf2 gene. Yeast 12(12):1239-50