Standard Name	POT1 1 (see Nomenclature conflict Note)
Systematic Name	YIL160C
Alias	FOX3 2 , POX3
Feature Type	ORF, Verified
Description	3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids (3)
Name Description	Peroxisomal Oxoacyl Thiolase 1

Chromosomal Location	ChrIX:41444 to 40191 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.

	View Computational GO annotations for POT1
Molecular Function
Manually curated	acetyl-CoA C-acyltransferase activity (IDA) mRNA binding (IDA)
Biological Process
Manually curated	fatty acid beta-oxidation (IMP)
Cellular Component
Manually curated	mitochondrial intermembrane space (IDA) peroxisomal matrix (IDA, IMP, ISM) peroxisome (IDA)

Pathways	fatty acid oxidation pathway

Classical genetics
null	resistance to methyl methanesulfonate: decreased utilization of carbon source: decreased
Large-scale survey
null	competitive fitness: increased competitive fitness: decreased metal resistance: decreased resistance to oleate: decreased resistance to quinine: decreased resistance to benzo[a]pyrene: decreased resistance to benzo[a]pyrene: increased resistance to St. John's Wort extract: decreased stress resistance: decreased vegetative growth: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	83 total interaction(s) for 69 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-Western: 8 Co-crystal Structure: 2 Co-purification: 1 Reconstituted Complex: 2 Two-hybrid: 4
Genetic Interactions	Negative Genetic: 55 Phenotypic Enhancement: 1 Positive Genetic: 8 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrIX:41444 to 40191 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
Last Update	Coordinates: 1994-12-10 | Sequence: 1994-12-10
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1254 41444..40191 1994-12-10 1994-12-10
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000001422