YBR074W Summary

YBR074W Summary

Reserved Name	PFF1 1 This name is reserved with SGD according to the Gene Naming Guidelines agreed upon by the yeast community. For more information about this reservation, please see the Locus History.
Systematic Name	YBR074W
Alias	YBR075W
Feature Type	ORF, Uncharacterized
Description	Putative metalloprotease (2)
Name Description	Protease in FXNA-related Family 1

Chromosomal Location	ChrII:386286 to 389216 \| ORF Map \| GBrowse

Gene Ontology Annotations All YBR074W GO evidence and references

	View Computational GO annotations for YBR074W
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
Manually curated	cellular_component unknown (ND)

Mutant phenotypes All YBR074W Phenotype evidence and references

Classical genetics
null	resistance to sodium dodecyl sulfate: decreased resistance to KL114 (Congo Red mimetic): decreased
Large-scale survey
null	competitive fitness: decreased sporulation: abnormal starvation resistance: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY \| SCMD \| ScreenTroll \| Yeast Fitness Database

interactions All YBR074W Interaction evidence and references

	7 total interaction(s) for 7 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Reconstituted Complex: 1
Genetic Interactions	Negative Genetic: 4 Positive Genetic: 1
Resources	BioGRID \| BOND \| BioPIXIE \| CYC2008 (complexes) \| Complexome \| DIP \| DRYGIN \| GeneMANIA \| InterologFinder

Expression Summary


Resources	Expression Summary \| Cell cycle and metabolic oscillation \| Cell cycle transcript profile \| Cyclebase \| Genevestigator \| GermOnline \| SPELL \| YMGV \| YeastFunc

Protein Information All YBR074W Protein evidence and references

Localization	YPL+ \| YeastGFP
Phosphorylation	PhosphoGRID \| PhosphoPep Database
Structure	GPMDB \| SCOP
Homologs	Ashbya (AGD) \| AspGD Homologs \| CGD Homologs \| CandidaDB Homologs \| Fungal Orthogroups Repository \| P-POD \| PDB Homologs \| PhylomeDB \| YGOB \| YOGY

sequence information

ChrII:386286 to 389216 | |

This feature contains embedded feature(s): YBR075W

SGD ORF map

Last Update

Coordinates: 2011-02-03 | Sequence: 2011-02-03

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..2931	386286..389216	2011-02-03	2011-02-03

Retrieve sequences

Analyze Sequence

S288C only	BLASTP \| ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes \| Six-Frame Translation
S288C vs. other species	Fungal Alignment \| BLASTN vs. fungi \| BLASTP at NCBI \| BLASTP vs. fungi \| Synteny Viewer
S288C vs. other strains	Strain Alignment

Resources

External Links	All Associated Seq \| E.C. \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| Search all NCBI (Entrez)

Primary SGDID	S000000278

References cited on this page View Complete Literature Guide for YBR074W

1)	Hecht KA, et al. (2013) Characterization of an M28 metalloprotease family member residing in the yeast vacuole FEMS Yeast Res ()
2)	Jonson L, et al. (2004) Enhanced peptide secretion by gene disruption of CYM1, a novel protease in Saccharomyces cerevisiae. Eur J Biochem 271(23-24):4788-97