SEA4/YBL104C Summary Help

Standard Name SEA4 1
Systematic Name YBL104C
Alias YBL103C-A
Feature Type ORF, Verified
Description Subunit of the SEA (Seh1-associated) complex; SEA is a coatomer-related complex that associates dynamically with the vacuole; has an N-terminal beta-propeller fold and a C-terminal RING motif; promoter contains multiple GCN4 binding sites (1, 2)
Name Description SEh1-Associated 1
Chromosomal Location
ChrII:21293 to 18177 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All SEA4 GO evidence and references
  View Computational GO annotations for SEA4
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Large-scale survey
null
Resources
78 total interaction(s) for 64 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 30
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 1
  • Protein-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 1
  • Negative Genetic: 28
  • Phenotypic Enhancement: 5
  • Positive Genetic: 8
  • Synthetic Growth Defect: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 1,038
Molecular Weight (Da) 117,635
Isoelectric Point (pI) 6
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrII:21293 to 18177 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
This feature contains embedded feature(s): YBL103C-A
SGD ORF map
Last Update Coordinates: 2004-01-26 | Sequence: 2004-01-26
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3117 21293..18177 2004-01-26 2004-01-26
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000000200
References cited on this page View Complete Literature Guide for SEA4
1) Dokudovskaya S, et al.  (2011) A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. Mol Cell Proteomics 10(6):M110.006478
2) Schuldiner O, et al.  (1998) Computer analysis of the entire budding yeast genome for putative targets of the GCN4 transcription factor. Curr Genet 33(1):16-20