SUI1/YNL244C Summary Help

SUI1 BASIC INFORMATION

Standard Name SUI1 1
Systematic Name YNL244C
Alias MOF2 2 , RFR1
Feature Type ORF, Verified
Description Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phase (2, 3, 4, 5)
Name Description SUppressor of Initiator codon 1
GO Annotations All SUI1 GO evidence and references
    View Computational GO annotations for SUI1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All SUI1 Phenotype details and references
Classical genetics
conditional
Large-scale survey
conditional
null
Interactions SUI1 All interactions details and references
109 total interaction(s) for 52 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 43
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 25
  • Co-fractionation: 4
  • Co-purification: 1
  • Reconstituted Complex: 15
  • Two-hybrid: 10
Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Phenotypic Suppression: 1
  • Synthetic Lethality: 4
  • Synthetic Rescue: 2
Sequence Information
ChrXIV:187497 to 187171 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -171 cM
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..327 187497..187171 2005-11-07 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005188

SUI1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Protein Info & Structure
  • Localization Resources
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  • Phenotype Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for SUI1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for SUI1]

1) Donahue TF, et al.  (1988) Mutations at a Zn(II) finger motif in the yeast eIF-2 beta gene alter ribosomal start-site selection during the scanning process. Cell 54(5):621-32
2) Cui Y, et al.  (1998) The Mof2/Sui1 protein is a general monitor of translational accuracy. Mol Cell Biol 18(3):1506-16
3) Naranda T, et al.  (1996) SUI1/p16 is required for the activity of eukaryotic translation initiation factor 3 in Saccharomyces cerevisiae. Mol Cell Biol 16(5):2307-13
4) Yoon HJ and Donahue TF  (1992) The suil suppressor locus in Saccharomyces cerevisiae encodes a translation factor that functions during tRNA(iMet) recognition of the start codon. Mol Cell Biol 12(1):248-60
5) Harger JW and Dinman JD  (2004) Evidence against a direct role for the Upf proteins in frameshifting or nonsense codon readthrough. RNA 10(11):1721-9