HMF1/YER057C Summary

HMF1 BASIC INFORMATION

Standard Name	HMF1
Systematic Name	YER057C
Alias	HIG1
Feature Type	ORF, Verified
Description	Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro (1, 2)
Name Description	Homologous Mmf1p Factor 1

GO Annotations	All HMF1 GO evidence and references
	View Computational GO annotations for HMF1
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	biological_process unknown (ND)
Cellular Component
Manually curated	cytoplasm (IDA) cytosol (IDA) nucleus (IDA)

Mutant Phenotype	All HMF1 Phenotype details and references
Large-scale survey
null	transposable element transposition: increased viable

Interactions	HMF1 All interactions details and references
	3 total interaction(s) for 3 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1 PCA: 1

Sequence Information

ChrV:271124 to 270735 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..390	271124..270735	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000000859

HMF1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for HMF1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for HMF1]

1)	Oxelmark E, et al. (2000) Mmf1p, a novel yeast mitochondrial protein conserved throughout evolution and involved in maintenance of the mitochondrial genome. Mol Cell Biol 20(20):7784-97
2)	Deaconescu AM, et al. (2002) X-ray structure of Saccharomyces cerevisiae homologous mitochondrial matrix factor 1 (Hmf1). Proteins 48(2):431-6

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