tI(GAU)Q Summary

tI(GAU)Q Summary

Systematic Name	tI(GAU)Q
Feature Type	tRNA
Description	Mitochondrial isoleucine tRNA (tRNA-Ile), predicted by tRNAscan-SE analysis; mutations in human ortholog are linked to conditions such as progressive encephalopathy, metabolic syndrome, and hypomagnesaemia (1, 2, 3)

Chromosomal Location	ChrMito:70162 to 70237 \| ORF Map \| GBrowse

Gene Ontology Annotations All tI(GAU)Q GO evidence and references


Molecular Function
Manually curated	triplet codon-amino acid adaptor activity (ISS)
Biological Process
Manually curated	translational elongation (NAS)
Cellular Component
Manually curated	mitochondrion (NAS)

Mutant phenotypes All tI(GAU)Q Phenotype evidence and references

Classical genetics
reduction of function	mitochondrial rho- mutation frequency: increased respiratory growth: absent

interactions All tI(GAU)Q Interaction evidence and references

	5 total interaction(s) for 3 unique genes/features.
Genetic Interactions	Dosage Rescue: 5
Resources	BioGRID

sequence information

ChrMito:70162 to 70237 | |

SGD ORF map

Last Update

Coordinates: 2000-05-19 | Sequence: 2000-05-19

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
Noncoding exon	1..76	70162..70237	2000-05-19	2000-05-19

Retrieve sequences

Analyze Sequence

S288C only	ATCC/WashU Clones \| BLASTN \| Design Primers \| Restriction Fragment Map \| Restriction Fragment Sizes
S288C vs. other species	BLASTN vs. fungi

Resources

External Links	All Associated Seq \| Search all NCBI (Entrez)

Primary SGDID	S000007322

References cited on this page View Complete Literature Guide for

1)	Foury F, et al. (1998) The complete sequence of the mitochondrial genome of Saccharomyces cerevisiae. FEBS Lett 440(3):325-31
2)	Montanari A, et al. (2011) Structural and functional role of bases 32 and 33 in the anticodon loop of yeast mitochondrial tRNAIle. RNA 17(11):1983-96
3)	Chan PP and Lowe TM (2009) GtRNAdb: a database of transfer RNA genes detected in genomic sequence. Nucleic Acids Res 37(Database issue):D93-7