SGF11/YPL047W Summary Help

Standard Name SGF11 1
Systematic Name YPL047W
Feature Type ORF, Verified
Description Integral subunit of SAGA histone acetyltransferase complex; regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation (1, 2)
Name Description SaGa associated Factor 11kDa 1
Chromosomal Location
ChrXVI:465962 to 466261 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All SGF11 GO evidence and references
  View Computational GO annotations for SGF11
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 64 genes
Resources
Classical genetics
null
Large-scale survey
null
Resources
425 total interaction(s) for 204 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 129
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 13
  • Biochemical Activity: 5
  • Co-crystal Structure: 2
  • Co-localization: 1
  • Reconstituted Complex: 3
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Rescue: 1
  • Negative Genetic: 152
  • Phenotypic Suppression: 2
  • Positive Genetic: 74
  • Synthetic Growth Defect: 8
  • Synthetic Lethality: 13
  • Synthetic Rescue: 19

Resources
Expression Summary
histogram
Resources
Length (a.a.) 99
Molecular Weight (Da) 11,285
Isoelectric Point (pI) 7.26
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:465962 to 466261 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..300 465962..466261 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005968
References cited on this page View Complete Literature Guide for SGF11
1) Powell DW, et al.  (2004) Cluster analysis of mass spectrometry data reveals a novel component of SAGA. Mol Cell Biol 24(16):7249-59
2) Ingvarsdottir K, et al.  (2005) H2B ubiquitin protease Ubp8 and Sgf11 constitute a discrete functional module within the Saccharomyces cerevisiae SAGA complex. Mol Cell Biol 25(3):1162-72