RIC1/YLR039C Summary Help

RIC1 BASIC INFORMATION

Standard Name RIC1 1
Systematic Name YLR039C
Feature Type ORF, Verified
Description Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes (2, 3)
Name Description RIbosome Control 1
GO Annotations All RIC1 GO evidence and references
    View Computational GO annotations for RIC1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All RIC1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions RIC1 All interactions details and references
837 total interaction(s) for 494 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 16
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2
  • Two-hybrid: 1

Genetic Interactions
  • Dosage Rescue: 7
  • Phenotypic Enhancement: 412
  • Phenotypic Suppression: 212
  • Synthetic Growth Defect: 22
  • Synthetic Lethality: 162
  • Synthetic Rescue: 2

Sequence Information
ChrXII:228597 to 225427 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3171 228597..225427 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000004029

RIC1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Comparison Resources
  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for RIC1]

1) Mizuta K, et al.  (1997) RIC1, a novel gene required for ribosome synthesis in Saccharomyces cerevisiae. Gene 187(2):171-8
2) Bensen ES, et al.  (2001) Ric1p and the Ypt6p GTPase function in a common pathway required for localization of trans-Golgi network membrane proteins. Mol Biol Cell 12(1):13-26
3) Siniossoglou S, et al.  (2000) Ric1p and Rgp1p form a complex that catalyses nucleotide exchange on Ypt6p. EMBO J 19(18):4885-94