NEW1/YPL226W Summary Help

NEW1 BASIC INFORMATION

Standard Name NEW1 1
Systematic Name YPL226W
Feature Type ORF, Verified
Description ATP binding cassette family member; Asn/Gln-rich rich region supports [NU+] prion formation and susceptibility to [PSI+] prion induction; homologous to mRNA export factor from S. pombe and similar protein from C. albicans (1, 2, 3, 4, 5)
Name Description Nu+ 1
GO Annotations All NEW1 GO evidence and references
    View Computational GO annotations for NEW1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Mutant Phenotype All NEW1 Phenotype details and references
Classical genetics
null
Large-scale survey
null
Interactions NEW1 All interactions details and references
86 total interaction(s) for 81 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 27
  • Affinity Capture-RNA: 1
  • Reconstituted Complex: 1

Genetic Interactions
  • Phenotypic Enhancement: 33
  • Phenotypic Suppression: 9
  • Synthetic Growth Defect: 15

Sequence Information
ChrXVI:121767 to 125357 | ORF Map | GBrowse
Gbrowse
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..3591 121767..125357 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000006147

NEW1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Protein Info & Structure
  • Localization Resources
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  • Phenotype Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for NEW1]

1) Santoso A, et al.  (2000) Molecular basis of a yeast prion species barrier. Cell 100(2):277-88
2) Sturtevant J, et al.  (1998) Disruption studies of a Candida albicans gene, ELF1: a member of the ATP-binding cassette family. Microbiology 144 ( Pt 8):2311-21
3) Decottignies A and Goffeau A  (1997) Complete inventory of the yeast ABC proteins. Nat Genet 15(2):137-45
4) Osherovich LZ and Weissman JS  (2001) Multiple Gln/Asn-rich prion domains confer susceptibility to induction of the yeast [PSI(+)] prion. Cell 106(2):183-94
5) Kozak L, et al.  (2002) Elf1p, a member of the ABC class of ATPases, functions as a mRNA export factor in Schizosacchromyces pombe. J Biol Chem 277(37):33580-9