FAP7/YDL166C Summary

FAP7 BASIC INFORMATION

Standard Name	FAP7
Systematic Name	YDL166C
Feature Type	ORF, Verified
Description	Essential NTPase required for small ribosome subunit synthesis, mediates processing of the 20S pre-rRNA at site D in the cytoplasm but associates only transiently with 43S preribosomes via Rps14p, may be the endonuclease for site D (1)
Name Description	Factor Activating Pos9 2

GO Annotations	All FAP7 GO evidence and references
	View Computational GO annotations for FAP7
Molecular Function
Manually curated	nucleoside-triphosphatase activity (IMP, ISS)
Biological Process
Manually curated	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IMP, IPI) response to oxidative stress (IMP) NOT ribosomal small subunit export from nucleus (IMP)
Cellular Component
Manually curated	cytoplasm (IMP) nucleus (IDA) NOT preribosome (IPI)

Mutant Phenotype	All FAP7 Phenotype details and references
Large-scale survey
null	inviable

Interactions	FAP7 All interactions details and references
	13 total interaction(s) for 11 unique genes/features.
Physical Interactions	Affinity Capture-MS: 4 Biochemical Activity: 6 Reconstituted Complex: 1 Two-hybrid: 2

Sequence Information

ChrIV:164043 to 163450 | |

Note: this feature is encoded on the Crick strand.

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..594	164043..163450	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000002325

FAP7 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for FAP7

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for FAP7]

1)	Granneman S, et al. (2005) The putative NTPase Fap7 mediates cytoplasmic 20S pre-rRNA processing through a direct interaction with Rps14. Mol Cell Biol 25(23):10352-64
2)	Juhnke H, et al. (2000) The essential protein fap7 is involved in the oxidative stress response of Saccharomyces cerevisiae. Mol Microbiol 35(4):936-48

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