CAN1/YEL063C Summary Help

CAN1 BASIC INFORMATION

Standard Name CAN1 1
Systematic Name YEL063C
Feature Type ORF, Verified
Description Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance (2, 3, 4, 5, 6)
Name Description CANavanine resistance 3
GO Annotations All CAN1 GO evidence and references
    View Computational GO annotations for CAN1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Mutant Phenotype All CAN1 Phenotype details and references
Large-scale survey
null
Interactions CAN1 All interactions details and references
52 total interaction(s) for 51 unique genes/features.
Physical Interactions
  • Co-localization: 2
  • Protein-RNA: 1
  • Two-hybrid: 46
Genetic Interactions
  • Dosage Growth Defect: 1
  • Synthetic Growth Defect: 2
Sequence Information
ChrV:33466 to 31694 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Genetic position: -50 cM
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates		 Chromosomal
Coordinates		 Most Recent Updates
Coordinates Sequence
CDS 1..1773 33466..31694 1996-07-31 1996-07-31
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | TCDB | UniProtKB
Primary SGDIDS000000789

CAN1 RESOURCES

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SGD ORF mapGBrowse
SGD ORF map
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  • Literature
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  • Sequence Analysis Tools
  • Protein Info & Structure
  • Localization Resources
  • Interactions
  • Phenotype Resources
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  • Functional Analysis

Click on histogram for expression summary
Expression Summary histogram

ADDITIONAL INFORMATION for CAN1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CAN1]

1) Link, A. and Olson, M.  (1989) Personal Communication, Mortimer Map Edition 10
2) Ahmad M and Bussey H  (1986) Yeast arginine permease: nucleotide sequence of the CAN1 gene. Curr Genet 10(8):587-92
3) Larimer FW, et al.  (1978) Mutagenicity of methylated N-nitrosopiperidines in Saccharomyces cerevisiae. Mutat Res 57(2):155-61
4) Broach JR, et al.  (1979) Transformation in yeast: development of a hybrid cloning vector and isolation of the CAN1 gene. Gene 8(1):121-33
5) Opekarova M, et al.  (2002) Phosphatidyl ethanolamine is essential for targeting the arginine transporter Can1p to the plasma membrane of yeast. Biochim Biophys Acta 1564(1):9-13
6) Malinska K, et al.  (2003) Visualization of protein compartmentation within the plasma membrane of living yeast cells. Mol Biol Cell 14(11):4427-36