Standard Name	AZF1 1
Systematic Name	YOR113W
Feature Type	ORF, Verified
Description	Zinc-finger transcription factor; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity (1, 2, 3, 4, 5, 6)
Name Description	Asparagine-rich Zinc-Finger 1

Chromosomal Location	ChrXV:534075 to 536819 | ORF Map | GBrowse

	View Computational GO annotations for AZF1
Molecular Function
Manually curated	RNA polymerase II core promoter proximal region sequence-specific DNA binding (IDA, IMP) RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription (IDA, IMP)
High-throughput	sequence-specific DNA binding (IDA)
Biological Process
Manually curated	cellular response to carbohydrate stimulus (IMP) regulation of fungal-type cell wall organization (IMP) regulation of transcription from RNA polymerase II promoter (IDA, IMP)
Cellular Component
Manually curated	nucleus (IDA)

Binding motifs	Predicted AZF1 Binding Site Locations
	BTTCTTTTB 7 [Search intergenic regions for BTTCTTTTB] TTTTTCTT 3 [Search intergenic regions for TTTTTCTT] YWTTKCKKTYYCKGYKKY 8 [Search intergenic regions for YWTTKCKKTYYCKGYKKY]
Regulatory modules	predicted: stressResponse (571)
Resources	ScerTF | YEASTRACT | YeTFaSCo

Classical genetics
null	viable
Large-scale survey
null	anaerobic growth: decreased competitive fitness: decreased haploproficient resistance to nickel sulfate: increased vacuolar morphology: abnormal vegetative growth: abnormal viable
overexpression	vegetative growth: decreased rate
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	71 total interaction(s) for 61 unique genes/features.
Physical Interactions	Affinity Capture-MS: 5 Affinity Capture-RNA: 2 Biochemical Activity: 7 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 5 Negative Genetic: 47 Positive Genetic: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXV:534075 to 536819 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2745 534075..536819 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain M22 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005639