ZEO1/YOL109W Summary Help

Standard Name ZEO1 1
Systematic Name YOL109W
Feature Type ORF, Verified
Description Peripheral membrane protein of the plasma membrane; interacts with Mid2p; regulates the cell integrity pathway mediated by Pkc1p and Slt2p; the authentic protein is detected in a phosphorylated state in highly purified mitochondria (2, 3)
Name Description ZEOcin resistance 1
Chromosomal Location
ChrXV:110297 to 110638 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All ZEO1 GO evidence and references
Molecular Function
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 20 genes
Resources
Large-scale survey
null
overexpression
Resources
49 total interaction(s) for 40 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 16
  • Affinity Capture-RNA: 3
  • PCA: 1
  • Two-hybrid: 3

Genetic Interactions
  • Dosage Growth Defect: 3
  • Dosage Rescue: 1
  • Negative Genetic: 16
  • Positive Genetic: 3
  • Synthetic Lethality: 1
  • Synthetic Rescue: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 113
Molecular Weight (Da) 12,589
Isoelectric Point (pI) 5.24
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:110297 to 110638 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..342 110297..110638 2006-01-05 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005469
References cited on this page View Complete Literature Guide for ZEO1
1) Cinato E, et al.  (2002) A DNA microarray-based approach to elucidate the effects of the immunosuppressant SR31747A on gene expression in Saccharomyces cerevisiae. Gene Expr 10(5-6):213-30
2) Green R, et al.  (2003) A synthetic analysis of the Saccharomyces cerevisiae stress sensor Mid2p, and identification of a Mid2p-interacting protein, Zeo1p, that modulates the PKC1-MPK1 cell integrity pathway. Microbiology 149(Pt 9):2487-99
3) Reinders J, et al.  (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906