Standard Name	YVC1 1
Systematic Name	YOR087W
Alias	YOR088W
Feature Type	ORF, Verified
Description	Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic shock (1, 2) Also known as: TRPY1 3
Name Description	Yeast Vacuolar Conductance 1

Chromosomal Location	ChrXV:487707 to 489734 | ORF Map | GBrowse

	View Computational GO annotations for YVC1
Molecular Function
Manually curated	calcium activated cation channel activity (IDA) calcium channel activity (IDA) potassium channel activity (IDA) sodium channel activity (IDA) voltage-gated ion channel activity (IDA)
Biological Process
Manually curated	cellular cation homeostasis (IDA, IMP)
Cellular Component
Manually curated	fungal-type vacuole (IDA) fungal-type vacuole membrane (IDA)

Classical genetics
null	viable
Large-scale survey
null	polyphosphate accumulation: abnormal competitive fitness: normal haploinsufficient vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	33 total interaction(s) for 32 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1 PCA: 3 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 21 Phenotypic Suppression: 6
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DIP | DRYGIN | GeneMANIA | InterologFinder | YeastRC Two-Hybrid

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXV:487707 to 489734 | ORF Map | GBrowse
	This feature contains embedded feature(s): YOR088W
Last Update	Coordinates: 2011-02-03 | Sequence: 2003-01-09
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..2028 487707..489734 2011-02-03 2003-01-09
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain T73 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain YPS163 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000005613