YTM1/YOR272W Summary Help

Standard Name YTM1 1
Systematic Name YOR272W
Alias CST14 2
Feature Type ORF, Verified
Description Constituent of 66S pre-ribosomal particles; forms a complex with Nop7p and Erb1p that is required for maturation of the large ribosomal subunit; has seven C-terminal WD repeats (3, 4, 5)
Chromosomal Location
ChrXV:832813 to 834195 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YTM1 GO evidence and references
  View Computational GO annotations for YTM1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 5 genes
Resources
Classical genetics
conditional
Large-scale survey
null
overexpression
reduction of function
Resources
180 total interaction(s) for 75 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 147
  • Affinity Capture-Western: 20
  • Biochemical Activity: 1
  • Reconstituted Complex: 2
  • Two-hybrid: 2

Genetic Interactions
  • Dosage Growth Defect: 1
  • Positive Genetic: 1
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 4

Resources
Expression Summary
histogram
Resources
Length (a.a.) 460
Molecular Weight (Da) 51,358
Isoelectric Point (pI) 6.95
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:832813 to 834195 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1383 832813..834195 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005798
References cited on this page View Complete Literature Guide for YTM1
1) Matsumoto, S. and Yahara, I.,  (1997) YTM1, a suppressor of beta-tubulin mutation, encodes a novel microtubule-interacting protein and is essential for G1/S transition in Saccharomyces cerevisiae. Unpublished
2) Ouspenski II, et al.  (1999) New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability. Nucleic Acids Res 27(15):3001-8
3) Harnpicharnchai P, et al.  (2001) Composition and functional characterization of yeast 66S ribosome assembly intermediates. Mol Cell 8(3):505-15
4) Horsey EW, et al.  (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27
5) Miles TD, et al.  (2005) Ytm1, Nop7, and Erb1 form a complex necessary for maturation of yeast 66S preribosomes. Mol Cell Biol 25(23):10419-32