Standard Name	YTA7 1
Systematic Name	YGR270W
Feature Type	ORF, Verified
Description	Protein that localizes to chromatin; has a role in regulation of histone gene expression; has a bromodomain-like region that interacts with the N-terminal tail of histone H3, and an ATPase domain; relocalizes to the cytosol in response to hypoxia; potentially phosphorylated by Cdc28p (2, 3, 4, 5, 6)
Name Description	Yeast Tat-binding Analog 1

Chromosomal Location	ChrVII:1027370 to 1031509 | ORF Map | GBrowse

	View Computational GO annotations for YTA7
Molecular Function
Manually curated	chromatin binding (IDA, IMP) histone binding (IDA, IMP)
Biological Process
Manually curated	negative regulation of chromatin silencing (IMP) negative regulation of transcription from RNA polymerase II promoter (IMP) positive regulation of transcription from RNA polymerase II promoter (IMP)
Cellular Component
Manually curated	cytosol (IDA) extrinsic to endoplasmic reticulum membrane (IDA) nucleus (IDA)
High-throughput	nucleus (IDA)

Classical genetics
null	squalene accumulation: increased lanosterol accumulation: increased chromosome/plasmid maintenance: abnormal colony appearance: abnormal cis-prenyltransferase activity: increased resistance to lovastatin: decreased silencing: increased
Large-scale survey
null	cell cycle progression in G1 phase: increased duration polyphosphate accumulation: abnormal chronological lifespan: increased competitive fitness: decreased filamentous growth: decreased heat sensitivity: increased invasive growth: absent Hta1p-GFP accumulation: decreased resistance to ethanol: decreased resistance to tunicamycin: increased resistance to mycophenolic acid: increased resistance to methyl methanesulfonate: increased resistance to bleomycin: increased resistance to quinine: increased resistance to acetic acid: increased resistance to hydroxyurea: decreased resistance to BPS: decreased resistance to arsenite(3-): decreased resistance to cycloheximide: decreased resistance to fluconazole: decreased resistance to fenpropimorph: decreased resistance to caffeine: decreased resistance to acrolein: decreased stress resistance: decreased telomere length: decreased transposable element transposition: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	484 total interaction(s) for 300 unique genes/features.
Physical Interactions	Affinity Capture-MS: 116 Affinity Capture-RNA: 2 Affinity Capture-Western: 2 Biochemical Activity: 1 Co-fractionation: 1 Co-localization: 2 PCA: 1 Protein-peptide: 2 Reconstituted Complex: 2 Two-hybrid: 12
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 268 Phenotypic Enhancement: 4 Phenotypic Suppression: 6 Positive Genetic: 25 Synthetic Growth Defect: 32 Synthetic Lethality: 6 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVII:1027370 to 1031509 | ORF Map | GBrowse
	This feature contains embedded feature(s): YGR270C-A
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..4140 1027370..1031509 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI1631 S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000003502