RRP15/YPR143W Summary Help

Standard Name RRP15 1
Systematic Name YPR143W
Feature Type ORF, Verified
Description Nucleolar protein; constituent of pre-60S ribosomal particles; required for proper processing of the 27S pre-rRNA at the A3 and B1 sites to yield mature 5.8S and 25S rRNAs (1, 2)
Name Description Ribosomal RNA Processing 1
Chromosomal Location
ChrXVI:818323 to 819075 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RRP15 GO evidence and references
  View Computational GO annotations for RRP15
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Classical genetics
repressible
Large-scale survey
null
reduction of function
Resources
74 total interaction(s) for 69 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 43
  • Affinity Capture-RNA: 3
  • Biochemical Activity: 4
  • PCA: 1
  • Two-hybrid: 3

Genetic Interactions
  • Negative Genetic: 18
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 250
Molecular Weight (Da) 28,212
Isoelectric Point (pI) 5.54
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:818323 to 819075 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..753 818323..819075 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006347
References cited on this page View Complete Literature Guide for RRP15
1) De Marchis ML, et al.  (2005) Rrp15p, a novel component of pre-ribosomal particles required for 60S ribosome subunit maturation. RNA 11(4):495-502
2) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91