Standard Name	ARO7 1
Systematic Name	YPR060C
Alias	HGS1 2 , OSM2 1 , TYR7
Feature Type	ORF, Verified
Description	Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis (1, 3)
Name Description	AROmatic amino acid requiring

Chromosomal Location	ChrXVI:675631 to 674861 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 39.4 cM

	View Computational GO annotations for ARO7
Molecular Function
Manually curated	chorismate mutase activity (IDA)
Biological Process
Manually curated	L-phenylalanine biosynthetic process (IC, IMP) tyrosine biosynthetic process (IC, IMP)
Cellular Component
High-throughput	cytoplasm (IDA) nucleus (IDA)

Pathways	pathways of chorismate phenylalanine biosynthesis superpathway of phenylalanine, tyrosine and tryptophan biosynthesis tyrosine biosynthesis

Classical genetics
activation	vegetative growth: decreased rate
null	auxotrophy resistance to 2-phenylethanol: decreased
unspecified	resistance to 2-phenylethanol: decreased resistance to mercury dichloride: decreased
Large-scale survey
null	competitive fitness: decreased fermentative growth: decreased rate haploinsufficient hyperosmotic stress resistance: decreased resistance to selenomethionine: increased resistance to ethanol: decreased resistance to methyl methanesulfonate: decreased resistance to 4-chlorophenol: decreased resistance to 2,4-dichlorophenol: decreased resistance to pentachlorophenol: decreased resistance to spermine: decreased resistance to hygromycin B: decreased resistance to sorbate: decreased vacuolar morphology: abnormal viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	146 total interaction(s) for 113 unique genes/features.
Physical Interactions	Co-crystal Structure: 2
Genetic Interactions	Dosage Rescue: 1 Negative Genetic: 117 Phenotypic Suppression: 1 Positive Genetic: 18 Synthetic Growth Defect: 3 Synthetic Lethality: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXVI:675631 to 674861 | ORF Map | GBrowse
	Note: this feature is encoded on the Crick strand.
	Genetic position: 39.4 cM
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..771 675631..674861 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain CLIB324 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain Y10 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000006264