THI21/YPL258C Summary Help

Standard Name THI21 1
Systematic Name YPL258C
Feature Type ORF, Verified
Description Hydroxymethylpyrimidine (HMP) and HMP-phosphate kinase; involved in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p (1, 2)
Name Description THIamine metabolism 1
Chromosomal Location
ChrXVI:55153 to 53498 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All THI21 GO evidence and references
  View Computational GO annotations for THI21
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 1 genes
Resources
Pathways
Large-scale survey
null
overexpression
unspecified
Resources
17 total interaction(s) for 16 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Protein-peptide: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 6
  • Phenotypic Enhancement: 2
  • Positive Genetic: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 551
Molecular Weight (Da) 61,334
Isoelectric Point (pI) 5.82
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:55153 to 53498 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1656 55153..53498 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006179
References cited on this page View Complete Literature Guide for THI21
1) Llorente B, et al.  (1999) Genetic redundancy and gene fusion in the genome of the Baker's yeast Saccharomyces cerevisiae: functional characterization of a three-member gene family involved in the thiamine biosynthetic pathway. Mol Microbiol 32(6):1140-52
2) Kawasaki Y, et al.  (2005) Biosynthesis of hydroxymethylpyrimidine pyrophosphate in Saccharomyces cerevisiae. Curr Genet 47(3):156-62