BBP1/YPL255W Summary Help

Standard Name BBP1 1
Systematic Name YPL255W
Feature Type ORF, Verified
Description Protein required for the spindle pole body (SPB) duplication; localizes at the cytoplasmic side of the central plaque periphery of the SPB; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p (2, 3)
Name Description Bfr1 Binding Protein 1
Chromosomal Location
ChrXVI:67725 to 68882 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All BBP1 GO evidence and references
  View Computational GO annotations for BBP1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
conditional
null
overexpression
reduction of function
repressible
Resources
57 total interaction(s) for 38 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 3
  • Biochemical Activity: 1
  • Co-purification: 1
  • FRET: 3
  • Protein-peptide: 1
  • Reconstituted Complex: 6
  • Two-hybrid: 21

Genetic Interactions
  • Dosage Growth Defect: 1
  • Dosage Lethality: 1
  • Dosage Rescue: 4
  • Negative Genetic: 1
  • Phenotypic Suppression: 2
  • Synthetic Growth Defect: 3
  • Synthetic Lethality: 5
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 385
Molecular Weight (Da) 45,384
Isoelectric Point (pI) 6.46
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:67725 to 68882 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 1996-07-31 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1158 67725..68882 1996-07-31 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000006176
References cited on this page View Complete Literature Guide for BBP1
1) Xue Z, et al.  (1996) Yeast mutants that produce a novel type of ascus containing asci instead of spores. Genetics 144(3):979-89
2) Schramm C, et al.  (2000) The Bbp1p-Mps2p complex connects the SPB to the nuclear envelope and is essential for SPB duplication. EMBO J 19(3):421-33
3) Park CJ, et al.  (2004) Requirement for Bbp1p in the proper mitotic functions of Cdc5p in Saccharomyces cerevisiae. Mol Biol Cell 15(4):1711-23