AEP3/YPL005W Summary Help

Standard Name AEP3 1
Systematic Name YPL005W
Feature Type ORF, Verified
Description Peripheral mitochondrial inner membrane protein; may facilitate use of unformylated tRNA-Met in mitochondrial translation initiation; stabilizes the bicistronic AAP1-ATP6 mRNA (1, 2)
Name Description ATPase ExPression 1
Chromosomal Location
ChrXVI:548486 to 550306 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All AEP3 GO evidence and references
  View Computational GO annotations for AEP3
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 1 genes
Resources
Classical genetics
null
reduction of function
Large-scale survey
null
Resources
45 total interaction(s) for 44 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 2

Genetic Interactions
  • Negative Genetic: 22
  • Phenotypic Suppression: 1
  • Positive Genetic: 14
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 606
Molecular Weight (Da) 70,309
Isoelectric Point (pI) 10.53
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXVI:548486 to 550306 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1821 548486..550306 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005926
References cited on this page View Complete Literature Guide for AEP3
1) Ellis TP, et al.  (2004) Aep3p stabilizes the mitochondrial bicistronic mRNA encoding subunits 6 and 8 of the H+-translocating ATP synthase of Saccharomyces cerevisiae. J Biol Chem 279(16):15728-33
2) Lee C, et al.  (2009) Yeast AEP3p is an accessory factor in initiation of mitochondrial translation. J Biol Chem 284(49):34116-25