RIM20/YOR275C Summary Help

Standard Name RIM20 1
Systematic Name YOR275C
Feature Type ORF, Verified
Description Protein involved in proteolytic activation of Rim101p; part of response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation (1, 2)
Name Description Regulator of IME2 3
Chromosomal Location
ChrXV:841069 to 839084 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All RIM20 GO evidence and references
  View Computational GO annotations for RIM20
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 6 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
233 total interaction(s) for 159 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-Western: 1
  • Biochemical Activity: 1
  • Co-purification: 1
  • PCA: 1
  • Two-hybrid: 11

Genetic Interactions
  • Dosage Growth Defect: 2
  • Dosage Lethality: 2
  • Negative Genetic: 151
  • Positive Genetic: 24
  • Synthetic Growth Defect: 28
  • Synthetic Lethality: 10

Resources
Expression Summary
histogram
Resources
Length (a.a.) 661
Molecular Weight (Da) 75,947
Isoelectric Point (pI) 5.76
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:841069 to 839084 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1986 841069..839084 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005801
References cited on this page View Complete Literature Guide for RIM20
1) Xu W and Mitchell AP  (2001) Yeast PalA/AIP1/Alix homolog Rim20p associates with a PEST-like region and is required for its proteolytic cleavage. J Bacteriol 183(23):6917-23
2) Xu W, et al.  (2004) Multivesicular body-ESCRT components function in pH response regulation in Saccharomyces cerevisiae and Candida albicans. Mol Biol Cell 15(12):5528-37
3) Su SS and Mitchell AP  (1993) Identification of functionally related genes that stimulate early meiotic gene expression in yeast. Genetics 133(1):67-77