TRE2/YOR256C Summary Help

Standard Name TRE2 1
Systematic Name YOR256C
Feature Type ORF, Verified
Description Transferrin receptor-like protein; functions with Tre1p to regulate ubiquitylation and vacuolar degradation of the metal transporter Smf1p; inviability of null mutant in systematic studies is due to proximity to CDC31; TRE2 has a paralog, TRE1, that arose from the whole genome duplication (1, 2, 3)
Name Description Transferrrin REceptor like 1
Chromosomal Location
ChrXV:810683 to 808254 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All TRE2 GO evidence and references
  View Computational GO annotations for TRE2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 5 genes
Resources
Classical genetics
null
Large-scale survey
null
reduction of function
repressible
Resources
9 total interaction(s) for 7 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5

Genetic Interactions
  • Dosage Rescue: 1
  • Synthetic Growth Defect: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 809
Molecular Weight (Da) 91,995
Isoelectric Point (pI) 5.27
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:810683 to 808254 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2006-01-05 | Sequence: 2011-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2430 810683..808254 2006-01-05 2011-02-03
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005782
References cited on this page View Complete Literature Guide for TRE2
1) Stimpson HE, et al.  (2006) Transferrin receptor-like proteins control the degradation of a yeast metal transporter. EMBO J 25(4):662-72
2) Poirey R and Jauniaux JC  (1997) Sequencing analysis of a 36.8 kb fragment of yeast chromosome XV reveals 26 open reading frames including SEC63, CDC31, SUG2, GCD1, RBL2, PNT1, PAC1 and VPH1. Yeast 13(5):483-7
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61