NOC2/YOR206W Summary Help

Standard Name NOC2 1
Systematic Name YOR206W
Feature Type ORF, Verified
Description Protein that forms a nucleolar complex with Mak21p; binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors (1)
Name Description NucleOlar Complex associated 1
Chromosomal Location
ChrXV:727512 to 729644 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All NOC2 GO evidence and references
  View Computational GO annotations for NOC2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 84 genes
Resources
Classical genetics
null
Large-scale survey
conditional
null
overexpression
reduction of function
Resources
198 total interaction(s) for 98 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 164
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 9
  • Co-purification: 1
  • PCA: 12
  • Reconstituted Complex: 1
  • Two-hybrid: 1

Genetic Interactions
  • Synthetic Growth Defect: 1
  • Synthetic Lethality: 7

Resources
Expression Summary
histogram
Resources
Length (a.a.) 710
Molecular Weight (Da) 81,601
Isoelectric Point (pI) 8.94
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:727512 to 729644 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2133 727512..729644 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005732
References cited on this page View Complete Literature Guide for NOC2
1) Milkereit P, et al.  (2001) Maturation and intranuclear transport of pre-ribosomes requires Noc proteins. Cell 105(4):499-509