MDM32/YOR147W Summary Help

Standard Name MDM32 1
Systematic Name YOR147W
Feature Type ORF, Verified
Description Mitochondrial inner membrane protein with similarity to Mdm31p; required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34 (2)
Name Description Mitochondrial Distribution and Morphology 1
Chromosomal Location
ChrXV:606607 to 608475 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All MDM32 GO evidence and references
  View Computational GO annotations for MDM32
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 3 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
255 total interaction(s) for 215 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 1
  • PCA: 1
  • Protein-RNA: 1
  • Two-hybrid: 1

Genetic Interactions
  • Negative Genetic: 167
  • Phenotypic Enhancement: 2
  • Positive Genetic: 51
  • Synthetic Growth Defect: 8
  • Synthetic Lethality: 14

Resources
Expression Summary
histogram
Resources
Length (a.a.) 622
Molecular Weight (Da) 72,027
Isoelectric Point (pI) 10.02
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:606607 to 608475 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2005-11-30
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1869 606607..608475 2011-02-03 2005-11-30
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005673
References cited on this page View Complete Literature Guide for MDM32
1) Dimmer KS, et al.  (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53
2) Dimmer KS, et al.  (2005) Mdm31 and Mdm32 are inner membrane proteins required for maintenance of mitochondrial shape and stability of mitochondrial DNA nucleoids in yeast. J Cell Biol 168(1):103-15