RGS2/YOR107W Summary Help

Standard Name RGS2 1
Systematic Name YOR107W
Feature Type ORF, Verified
Description Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p (1)
Name Description Regulator of heterotrimeric G protein Signaling 1
Chromosomal Location
ChrXV:521353 to 522282 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RGS2 GO evidence and references
  View Computational GO annotations for RGS2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
overexpression
Resources
13 total interaction(s) for 13 unique genes/features.
Physical Interactions
  • Affinity Capture-RNA: 3
  • Affinity Capture-Western: 1
  • Biochemical Activity: 4
  • Reconstituted Complex: 1

Genetic Interactions
  • Negative Genetic: 2
  • Positive Genetic: 2

Resources
Expression Summary
histogram
Resources
Length (a.a.) 309
Molecular Weight (Da) 35,100
Isoelectric Point (pI) 8.53
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:521353 to 522282 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..930 521353..522282 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005633
References cited on this page View Complete Literature Guide for RGS2
1) Versele M, et al.  (1999) A novel regulator of G protein signalling in yeast, Rgs2, downregulates glucose-activation of the cAMP pathway through direct inhibition of Gpa2. EMBO J 18(20):5577-91