Standard Name	YOR1 1
Systematic Name	YGR281W
Alias	YRS1 2
Feature Type	ORF, Verified
Description	Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter mediates export of many different organic anions including oligomycin; similar to human cystic fibrosis transmembrane receptor (CFTR) (1, 2, 3, 4, 5)
Name Description	Yeast Oligomycin Resistance 1

Chromosomal Location	ChrVII:1052824 to 1057257 | ORF Map | GBrowse

	View Computational GO annotations for YOR1
Molecular Function
Manually curated	xenobiotic-transporting ATPase activity (TAS)
Biological Process
Manually curated	response to drug (TAS) transport (TAS)
Cellular Component
Manually curated	plasma membrane (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
reduction of function	resistance to oligomycin: decreased
Large-scale survey
null	competitive fitness: decreased haploinsufficient resistance to cycloheximide: decreased resistance to amitrole: decreased telomere length: increased viable
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	146 total interaction(s) for 135 unique genes/features.
Physical Interactions	Affinity Capture-MS: 22 Affinity Capture-RNA: 1 Biochemical Activity: 1 Co-fractionation: 2 PCA: 18 Two-hybrid: 1
Genetic Interactions	Dosage Rescue: 2 Negative Genetic: 84 Phenotypic Enhancement: 4 Phenotypic Suppression: 1 Positive Genetic: 4 Synthetic Growth Defect: 3 Synthetic Lethality: 2 Synthetic Rescue: 1
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DIP | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	YeastRC | Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | AspGD Homologs | CGD Homologs | CandidaDB Homologs | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrVII:1052824 to 1057257 | ORF Map | GBrowse
Last Update	Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..4434 1052824..1057257 2011-02-03 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain UC5 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | TCDB | UniProtKB

Primary SGDID	S000003513