Standard Name	DFG16 1
Systematic Name	YOR030W
Alias	ECM41 , ZRG12 2
Feature Type	ORF, Verified
Description	Probable multiple transmembrane protein; involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; is glycosylated and phosphorylated; interacts with Rim21p and Rim9p in the plasma membrane to form a pH-sensing complex in the Rim101 pathway and is required to maintain Rim21p levels; required for accumulation of processed Rim101p (1, 3, 4)
Name Description	Defective for Filamentous Growth 5

Chromosomal Location	ChrXV:386825 to 388684 | ORF Map | GBrowse

	View Computational GO annotations for DFG16
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	protein processing (IMP) pseudohyphal growth (IMP)
Cellular Component
Manually curated	plasma membrane (IDA)
High-throughput	integral to membrane (ISM)

Classical genetics
null	invasive growth: absent Rim21p accumulation: decreased Rim9p distribution: abnormal Rim21p distribution: abnormal
Large-scale survey
null	acid pH resistance: decreased competitive fitness: decreased endocytosis: decreased haploinsufficient heat sensitivity: increased hyperosmotic stress resistance: decreased Rim9p accumulation: decreased resistance to nickel sulfate: increased resistance to amitrole: decreased resistance to wortmannin: normal resistance to BPS: decreased resistance to chloroquine: decreased resistance to sirolimus: decreased resistance to cycloheximide: decreased stress resistance: increased toxin resistance: decreased viable
overexpression	vegetative growth: decreased
unspecified	resistance to Calcofluor White: increased
Resources	PROPHECY | SCMD | ScreenTroll | Yeast Fitness Database

	235 total interaction(s) for 169 unique genes/features.
Physical Interactions	Affinity Capture-RNA: 2 Affinity Capture-Western: 2 Two-hybrid: 1
Genetic Interactions	Negative Genetic: 172 Phenotypic Suppression: 4 Positive Genetic: 30 Synthetic Growth Defect: 20 Synthetic Lethality: 4
Resources	BioGRID | BOND | BioPIXIE | CYC2008 (complexes) | Complexome | DRYGIN | GeneMANIA | InterologFinder

Resources	Expression Summary | Cell cycle and metabolic oscillation | Cell cycle transcript profile | Cyclebase | Genevestigator | GermOnline | SPELL | YMGV | YeastFunc

Localization	Organelle DB (UMich) | YPL+ | YeastGFP
Phosphorylation	PhosphoGRID | PhosphoPep Database
Structure	GPMDB | SCOP | YeastRC
Homologs	Ashbya (AGD) | Fungal Orthogroups Repository | P-POD | PDB Homologs | PhylomeDB | YGOB | YOGY

	ChrXV:386825 to 388684 | ORF Map | GBrowse
Last Update	Coordinates: 2006-01-05 | Sequence: 1996-07-31
Subfeature details	Relative Coordinates Chromosomal Coordinates Most Recent Updates Coordinates Sequence CDS 1..1860 386825..388684 2006-01-05 1996-07-31
Retrieve sequences	S.c. Reference Strain S288C S.c. Strain AWRI796 S.c. Strain BY4741 S.c. Strain BY4742 S.c. Strain CBS7960 S.c. Strain CEN.PK113-7D S.c. Strain CLIB215 S.c. Strain EC1118 S.c. Strain EC9-8 S.c. Strain FL100 S.c. Strain FostersB S.c. Strain FostersO S.c. Strain JAY291 S.c. Strain Kyokai7 S.c. Strain LalvinQA23 S.c. Strain PW5 S.c. Strain RM11-1a S.c. Strain Sigma1278b S.c. Strain T7 S.c. Strain Vin13 S.c. Strain VL3 S.c. Strain W303 S.c. Strain YJM269 S.c. Strain YJM789 S.c. Strain ZTW1 ORF Genomic DNA ORF Translation Coding sequence (CDS)

S288C only	BLASTP | ATCC/WashU Clones | BLASTN | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species	Fungal Alignment | BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi | Synteny Viewer
S288C vs. other strains	Strain Alignment

External Links	All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB

Primary SGDID	S000005556