YOL057W Summary Help

Systematic Name YOL057W
Feature Type ORF, Verified
Description Dipeptidyl-peptidase III; cleaves dipeptides from the amino terminus of target proteins; highly active on synthetic substrate Arg-Arg-2-naphthylamide; mammalian ortholog may be a biomarker for some cancers (1, 2)
Chromosomal Location
ChrXV:220767 to 222902 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YOL057W GO evidence and references
  View Computational GO annotations for YOL057W
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 3 genes
Resources
Large-scale survey
null
Resources
13 total interaction(s) for 11 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 5
  • Co-purification: 1

Genetic Interactions
  • Dosage Growth Defect: 1
  • Negative Genetic: 6

Resources
Expression Summary
histogram
Resources
Length (a.a.) 711
Molecular Weight (Da) 80,510
Isoelectric Point (pI) 6.23
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXV:220767 to 222902 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..2136 220767..222902 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005418
References cited on this page View Complete Literature Guide for YOL057W
1) Baral PK, et al.  (2008) The First Structure of Dipeptidyl-peptidase III Provides Insight into the Catalytic Mechanism and Mode of Substrate Binding. J Biol Chem 283(32):22316-24
2) Jajcanin-Jozic N, et al.  (2010) Identification of the reactive cysteine residues in yeast dipeptidyl peptidase III. Biochimie 92(1):89-96