AIF1/YNR074C Summary Help

Standard Name AIF1 1
Systematic Name YNR074C
Alias CPD1
Feature Type ORF, Verified
Description Mitochondrial cell death effector; translocates to the nucleus in response to apoptotic stimuli, homolog of mammalian Apoptosis-Inducing Factor, putative reductase (1)
Name Description Apoptosis-Inducing Factor 1
Chromosomal Location
ChrXIV:778738 to 777602 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All AIF1 GO evidence and references
  View Computational GO annotations for AIF1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 2 genes
Resources
Classical genetics
null
overexpression
Large-scale survey
null
Resources
14 total interaction(s) for 14 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1

Genetic Interactions
  • Negative Genetic: 9
  • Phenotypic Enhancement: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 378
Molecular Weight (Da) 41,335
Isoelectric Point (pI) 7.48
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:778738 to 777602 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1997-01-28
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1137 778738..777602 2011-02-03 1997-01-28
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005357
References cited on this page View Complete Literature Guide for AIF1
1) Wissing S, et al.  (2004) An AIF orthologue regulates apoptosis in yeast. J Cell Biol 166(7):969-74