VNX1/YNL321W Summary

VNX1 BASIC INFORMATION

Standard Name	VNX1 1
Systematic Name	YNL321W
Feature Type	ORF, Verified
Description	Low affinity vacuolar membrane localized monovalent cation/H+ antiporter; member of the calcium exchanger (CAX) family; potential Cdc28p substrate (1, 2)
Name Description	Vacuolar Na+/H+ eXchanger 1

GO Annotations	All VNX1 GO evidence and references
	View Computational GO annotations for VNX1
Molecular Function
Manually curated	potassium:hydrogen antiporter activity (IMP) sodium:hydrogen antiporter activity (IMP)
Biological Process
Manually curated	potassium ion transport (IMP) sodium ion transport (IMP)
Cellular Component
Manually curated	fungal-type vacuole (IDA)

Mutant Phenotype	All VNX1 Phenotype details and references
Classical genetics
null	resistance to hygromycin B: decreased viable
Large-scale survey
null	viable

Interactions	VNX1 All interactions details and references
	9 total interaction(s) for 9 unique genes/features.
Physical Interactions	Affinity Capture-MS: 1 Affinity Capture-RNA: 1 Biochemical Activity: 2 Protein-RNA: 1 Two-hybrid: 2
Genetic Interactions	Phenotypic Enhancement: 1 Synthetic Growth Defect: 1

Sequence Information

ChrXIV:34695 to 37421 | |

Last Update

Coordinates: 1996-07-31 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..2727	34695..37421	1996-07-31	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005265

VNX1 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for VNX1

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for VNX1]

1)	Cagnac O, et al. (2007) Identification and Characterization of Vnx1p, a Novel Type of Vacuolar Monovalent Cation/H+ Antiporter of Saccharomyces cerevisiae. J Biol Chem 282(33):24284-93
2)	Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64

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