CAF120/YNL278W Summary

CAF120 BASIC INFORMATION

Standard Name	CAF120 1
Systematic Name	YNL278W
Feature Type	ORF, Verified
Description	Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation (1)
Name Description	CCR4 Associated Factor 1

GO Annotations	All CAF120 GO evidence and references
	View Computational GO annotations for CAF120
Molecular Function
Manually curated	molecular_function unknown (ND)
Biological Process
Manually curated	regulation of transcription from RNA polymerase II promoter (IPI)
Cellular Component
Manually curated	CCR4-NOT complex (IPI)

Mutant Phenotype	All CAF120 Phenotype details and references
Classical genetics
null	resistance to hydroxyurea: normal viable
Large-scale survey
null	viable

Interactions	CAF120 All interactions details and references
	24 total interaction(s) for 24 unique genes/features.
Physical Interactions	Affinity Capture-MS: 2 Affinity Capture-RNA: 1 Biochemical Activity: 2 Protein-RNA: 1
Genetic Interactions	Dosage Rescue: 2 Phenotypic Enhancement: 10 Phenotypic Suppression: 4 Synthetic Growth Defect: 1 Synthetic Lethality: 1

Sequence Information

ChrXIV:113271 to 116453 | |

Last Update

Coordinates: 2005-11-07 | Sequence: 1996-07-31

Subfeature details

	Relative Coordinates	Chromosomal Coordinates	Most Recent Updates
	Relative Coordinates	Chromosomal Coordinates	Coordinates	Sequence
CDS	1..3183	113271..116453	2005-11-07	1996-07-31

External Links	All Associated Seq \| Entrez Gene \| Entrez RefSeq Protein \| MIPS \| UniProtKB

Primary SGDID	S000005222

CAF120 RESOURCES

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SGD ORF map	GBrowse

Click on histogram for expression summary
Expression Summary

ADDITIONAL INFORMATION for CAF120

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for CAF120]

1)	Chen J, et al. (2001) Purification and characterization of the 1.0 MDa CCR4-NOT complex identifies two novel components of the complex. J Mol Biol 314(4):683-94

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