YIF1/YNL263C Summary Help

YIF1 BASIC INFORMATION

Standard Name YIF1
Systematic Name YNL263C
Feature Type ORF, Verified
Description Integral membrane protein required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles (1, 2, 3)
Name Description YIP1-Interacting Factor
GO Annotations All YIF1 GO evidence and references
    View Computational GO annotations for YIF1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Mutant Phenotype All YIF1 Phenotype details and references
Large-scale survey
null
reduction of function
repressible
Interactions YIF1 All interactions details and references
  View additional details at BioGRID
74 total interaction(s) for 49 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Affinity Capture-RNA: 1
  • Affinity Capture-Western: 5
  • Biochemical Activity: 4
  • Co-fractionation: 1
  • Co-purification: 2
  • Reconstituted Complex: 15
  • Two-hybrid: 30

Genetic Interactions
  • Dosage Rescue: 3
  • Negative Genetic: 12

Sequence Information
ChrXIV:147841 to 146897 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Last Update Coordinates: 2005-11-07 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..945 147841..146897 2005-11-07 1996-07-31
Post-translational Modifications PhosphoGRID | PhosphoPep Database
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | UniProtKB
Primary SGDIDS000005207

YIF1 RESOURCES

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SGD ORF map
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  • Functional Analysis

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Expression Summary histogram

REFERENCES CITED ON THIS PAGE [View Complete Literature Guide for YIF1]

1) Barrowman J, et al.  (2003) The Yip1p.Yif1p complex is required for the fusion competence of endoplasmic reticulum-derived vesicles. J Biol Chem 278(22):19878-84
2) Matern H, et al.  (2000) A novel Golgi membrane protein is part of a GTPase-binding protein complex involved in vesicle targeting. EMBO J 19(17):4485-92
3) Heidtman M, et al.  (2005) Yos1p is a novel subunit of the Yip1p-Yif1p complex and is required for transport between the endoplasmic reticulum and the Golgi complex. Mol Biol Cell 16(4):1673-83