RIO2/YNL207W Summary Help

Standard Name RIO2 1, 2
Systematic Name YNL207W
Feature Type ORF, Verified
Description Essential serine kinase involved in the processing of 20S pre-rRNA; involved in the processing of the 20S pre-rRNA into mature 18S rRNA; has similarity to Rio1p (1, 2)
Name Description RIght Open reading frame 3
Chromosomal Location
ChrXIV:255353 to 256630 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All RIO2 GO evidence and references
  View Computational GO annotations for RIO2
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
Regulators 4 genes
Resources
Classical genetics
null
Large-scale survey
null
reduction of function
Resources
206 total interaction(s) for 118 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 150
  • Affinity Capture-RNA: 2
  • Affinity Capture-Western: 10
  • Biochemical Activity: 2
  • Co-crystal Structure: 9
  • Co-fractionation: 11
  • Reconstituted Complex: 10

Genetic Interactions
  • Negative Genetic: 9
  • Positive Genetic: 3

Resources
Expression Summary
histogram
Resources
Length (a.a.) 425
Molecular Weight (Da) 49,124
Isoelectric Point (pI) 5
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:255353 to 256630 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..1278 255353..256630 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005151
References cited on this page View Complete Literature Guide for RIO2
1) Vanrobays E, et al.  (2003) Late cytoplasmic maturation of the small ribosomal subunit requires RIO proteins in Saccharomyces cerevisiae. Mol Cell Biol 23(6):2083-95
2) Geerlings TH, et al.  (2003) Rio2p, an evolutionarily conserved, low abundant protein kinase essential for processing of 20 S Pre-rRNA in Saccharomyces cerevisiae. J Biol Chem 278(25):22537-45
3) Angermayr M and Bandlow W  (1997) The type of basal promoter determines the regulated or constitutive mode of transcription in the common control region of the yeast gene pair GCY1/RIO1. J Biol Chem 272(50):31630-5