YNL155W Summary Help

Systematic Name YNL155W
Feature Type ORF, Verified
Description Protein of unknown function; contains a DHHC domain and an AN1-type zinc finger; predicted to have thiol-disulfide oxidoreductase active site; transcriptionally regulated by Rpn4p along with proteasome subunit genes; putative ortholog of human AIRAP, which stimulates proteasome activity in response to arsenic; protein abundance increases in response to DNA replication stress (1, 2, 3, 4)
Chromosomal Location
ChrXIV:342516 to 343340 | ORF Map | GBrowse
Gbrowse
Gene Ontology Annotations All YNL155W GO evidence and references
  View Computational GO annotations for YNL155W
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Classical genetics
null
Large-scale survey
null
Resources
31 total interaction(s) for 28 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 7
  • Affinity Capture-RNA: 1
  • Biochemical Activity: 7
  • Two-hybrid: 2

Genetic Interactions
  • Negative Genetic: 13
  • Positive Genetic: 1

Resources
Expression Summary
histogram
Resources
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:342516 to 343340 | ORF Map | GBrowse
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..825 342516..343340 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005099
References cited on this page View Complete Literature Guide for
1) Fetrow JS, et al.  (2001) Genomic-scale comparison of sequence- and structure-based methods of function prediction: does structure provide additional insight? Protein Sci 10(5):1005-14
2) Mitchell DA, et al.  (2006) Protein palmitoylation by a family of DHHC protein S-acyltransferases. J Lipid Res 47(6):1118-27
3) Brohee S, et al.  (2011) Unraveling networks of co-regulated genes on the sole basis of genome sequences. Nucleic Acids Res 39(15):6340-58
4) Tkach JM, et al.  (2012) Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress. Nat Cell Biol 14(9):966-76