CPT1/YNL130C Summary Help

Standard Name CPT1 1
Systematic Name YNL130C
Feature Type ORF, Verified
Description Cholinephosphotransferase; required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription; CPT1 has a paralog, EPT1, that arose from the whole genome duplication (1, 2, 3)
Name Description CholinePhosphoTransferase 1
Chromosomal Location
ChrXIV:380831 to 379558 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All CPT1 GO evidence and references
  View Computational GO annotations for CPT1
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
Manually curated
High-throughput
Regulators 4 genes
Resources
Pathways
Classical genetics
null
Large-scale survey
null
Resources
63 total interaction(s) for 57 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 2
  • Affinity Capture-RNA: 1
  • PCA: 22

Genetic Interactions
  • Negative Genetic: 28
  • Positive Genetic: 8
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 393
Molecular Weight (Da) 44,829
Isoelectric Point (pI) 6.57
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:380831 to 379558 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 2004-02-03
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..50 380831..380782 2011-02-03 2004-02-03
Intron 51..142 380781..380690 2011-02-03 2004-02-03
CDS 143..1274 380689..379558 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | E.C. | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005074
References cited on this page View Complete Literature Guide for CPT1
1) Hjelmstad RH and Bell RM  (1987) Mutants of Saccharomyces cerevisiae defective in sn-1,2-diacylglycerol cholinephosphotransferase. Isolation, characterization, and cloning of the CPT1 gene. J Biol Chem 262(8):3909-17
2) Morash SC, et al.  (1994) Studies employing Saccharomyces cerevisiae cpt1 and ept1 null mutants implicate the CPT1 gene in coordinate regulation of phospholipid biosynthesis. J Biol Chem 269(46):28769-76
3) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61