YNL108C Summary Help

Systematic Name YNL108C
Alias HUF 1
Feature Type ORF, Verified
Description Protein phosphatase; similar to prokaryotic phosphotransfer enzymes; null mutant shows alterations in glucose metabolism; GFP-fusion protein localizes to the cytoplasm and nucleus; YNL108C has a paralog, TFC7, that arose from the whole genome duplication (1, 2, 3, 4, 5)
Chromosomal Location
ChrXIV:419826 to 419014 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
Gbrowse
Gene Ontology Annotations All YNL108C GO evidence and references
Molecular Function
Manually curated
Biological Process
Manually curated
Cellular Component
High-throughput
Regulators 2 genes
Resources
Classical genetics
null
Large-scale survey
null
overexpression
Resources
17 total interaction(s) for 16 unique genes/features.
Physical Interactions
  • Affinity Capture-MS: 1
  • Biochemical Activity: 1

Genetic Interactions
  • Dosage Growth Defect: 5
  • Negative Genetic: 6
  • Synthetic Growth Defect: 2
  • Synthetic Lethality: 1
  • Synthetic Rescue: 1

Resources
Expression Summary
histogram
Resources
Length (a.a.) 270
Molecular Weight (Da) 30,748
Isoelectric Point (pI) 5.55
Localization
Phosphorylation PhosphoGRID | PhosphoPep Database
Structure
Homologs
sequence information
ChrXIV:419826 to 419014 | ORF Map | GBrowse
Note: this feature is encoded on the Crick strand.
SGD ORF map
Last Update Coordinates: 2011-02-03 | Sequence: 1996-07-31
Subfeature details
Relative
Coordinates
Chromosomal
Coordinates
Most Recent Updates
Coordinates Sequence
CDS 1..813 419826..419014 2011-02-03 1996-07-31
Retrieve sequences
Analyze Sequence
S288C only
S288C vs. other species
S288C vs. other strains
Resources
External Links All Associated Seq | Entrez Gene | Entrez RefSeq Protein | MIPS | Search all NCBI (Entrez) | UniProtKB
Primary SGDIDS000005052
References cited on this page View Complete Literature Guide for YNL108C
1) Manaud N, et al.  (1998) A chimeric subunit of yeast transcription factor IIIC forms a subcomplex with tau95. Mol Cell Biol 18(6):3191-200
2) Giaever G, et al.  (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91
3) Huh WK, et al.  (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
4) Byrne KP and Wolfe KH  (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61
5) Taylor NM, et al.  (2013) Structural and Functional Characterization of a Phosphatase Domain within Yeast General Transcription Factor IIIC. J Biol Chem 288(21):15110-20